General Information

  • ID:  hor003573
  • Uniprot ID:  P83933
  • Protein name:  Periviscerokinin-3
  • Gene name:  NA
  • Organism:  Blaberus craniifer (Death's head cockroach)
  • Family:  Periviscerokinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Blaberus (genus), Blaberinae (subfamily), Blaberidae (family), Blaberoidea (superfamily), Blattodea (order), Dictyoptera (superorder), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  GSSGMIPFPRV
  • Length:  11
  • Propeptide:  GSSGMIPFPRV
  • Signal peptide:  NA
  • Modification:  T11 Valine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003573_AF2.pdbhor003573_ESM.pdb

Physical Information

Mass: 132589 Formula: C51H82N14O14S
Absent amino acids: ACDEHKLNQTWY Common amino acids: GPS
pI: 10.55 Basic residues: 1
Polar residues: 4 Hydrophobic residues: 3
Hydrophobicity: 30 Boman Index: -555
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 61.82
Instability Index: 5214.55 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  10849006
  • Title:  Identification of Novel Periviscerokinins From Single Neurohaemal Release Sites in Insects MS/MS Fragmentation Complemented by Edman Degradation.
  • PubMed ID:  19257902
  • Title:  A proteomic approach for studying insect phylogeny: CAPA peptides of ancient insect taxa (Dictyoptera, Blattoptera) as a test case.